One of the major approaches of P.H.A.G.E. in 2013 is the establishment of a Therapeutic Phage Bank under a Memorandum of Understanding between P.H.A.G.E. and the Leibniz Institute DSMZ. P.H.A.G.E. is an initiative with high relevance for the society. The establishment of a Therapeutic Phage Bank within a renowned and securely funded biological resource centre that is experienced in phage biology will strongly support the goals of P.H.A.G.E. insofar as phages that might be or definitely are suitable for application in humans have to be kept safe, secure and authentic for future use. The infrastructural preconditions for running such a phage collection is given at the Leibniz Institute DSMZ. 


For the purpose of P.H.A.G.E. and the establishment of the Therapeutic Phage Bank the pdf Memorandum of Understanding (814 KB)  has been undersigned by the President of P.H.A.G.E. and the director of the DSMZ in May 2013. Associated is a document Material Transfer Agreement (32 KB) , the latter being a binding document for all those who are recipients of phages and their hosts from this special bank. Phages and their hosts from this bank are accompanied by this MTA:

Recipients must not use these phages and their hosts commercially unless authorized by the depositor to do so. Recipients are the end-user and must not pass on phages and their hosts to a third party. Phages of this bank are for laboratory use and must be further propagated under prescribed conditions required for therapeutic use. Should the phages and their hosts be mentioned in any kind of publication, the depositor must be informed before and cited.

Procedures and curatorship of the Therapeutic Phage Bank 

The bank is located within the building of the Leibniz Institute DSMZ in Braunschweig, Germany. Phages are preserved for long-term storage according to two established methods: storage in liquid nitrogen in multiple aliquots and as filter-dried phage solutions in vacuum-sealed glass ampoules. Methodology is according to the DSMZ SOPs ( The DSMZ is certified according to ISO 9001:2008. All routine quality control procedures will be applied with phages and hosts of this bank e.g., purity and titre controls. The Therapeutic Phage Bank is under curatorship of the DSMZ Department of Microorganisms, Dr. Christine Rohde, This email address is being protected from spambots. You need JavaScript enabled to view it..

Deposition with the Therapeutic Phage Bank and depositors’ rights 

Preconditions for deposit are that phages and their hosts are pure and that hosts are allocated to risk group 1 or 2 while RG 3 is excluded. Deposit does not cost anything. The depositor will receive two ampoules each of the preserved phage and host and can furthermore receive phage and host once a year for free. More requests by the depositor will have to be processed via the DSMZ-usual procedures ( The depositor will be informed about each request on the phage or host, but cannot place any distribution restrictions on phages or hosts: phages and hosts of this bank will be freely available to authorized recipients for a fee and according to the MTA. Unless a research cooperation is negotiated with the depositor, the DSMZ will not characterize and work on phages deposited for this bank, all phages are accepted independently of the degree of characterization e.g., morphology or genomic sequence.